January 27, 2005Interactive Cardiovascular and Thoracic SurgeryOpen Access

The effects of cardiac cooling under surface-induced hypothermia on the cardiac function in the in situ heart

View Full Paper

Ask AI

Bookmark

Why the study?

Does cardiac cooling under surface-induced hypothermia with or without vasodilators improve cardiac function and efficiency in an in situ heart model?

Population

Adult mongrel dogs (in situ heart model)

Comparison

Cardiac cooling under surface-induced… vs Normothermia

Design

Preclinical

Authors

YNYoshiharu NishimuraWakayama Medical University

Discussion

Member takes

Implication

Hypothesis-generating for 34°C cooling plus vasodilators in cardiac protection; leaves open human translation.

Structured PICO

Does cardiac cooling under surface-induced hypothermia with or without vasodilators improve cardiac function and efficiency in an in situ heart model?

Population

Adult mongrel dogs (in situ heart model)

Intervention

Cardiac cooling under surface-induced hypothermia with or without concurrent vasodilator administration

Comparator

Normothermia

Outcome

Mechanoenergetical parameters including Emax (contractility index), external work (EW), and systolic pressure volume area (PVA)-independent myocardial oxygen consumption (VO2)surrogate

Cardiac cooling to 34 degrees C combined with vasodilators provides inotropic and oxygen-saving effects in an in situ heart model.

Cite This Study

Yoshiharu Nishimura (2005) studied this question.

synapsesocial.com/papers/6a87f10b2d13770579f4c6ce https://doi.org/10.1510/icvts.2004.097188

View Full Paper

Ask AI

Bookmark

The effects of cardiac cooling under surface-induced hypothermia on the cardiac function in the in situ heart

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The effects of cardiac cooling under surface-induced hypothermia on the cardiac function in the in situ heart

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider