Why the study?
Does cardiac cooling affect contractility and the relation between O2 consumption and systolic pressure-volume area in dog left ventricle?
Does cardiac cooling affect contractility and the relation between O2 consumption and systolic pressure-volume area in dog left ventricle?
Cardiac cooling increases contractility (Emax) but does not increase the chemomechanical efficiency of the contractile machinery in the dog left ventricle.
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Cooling may augment canine LV contractility without efficiency loss; hypothesis-generating for human translation.
Suga et al. (1988) studied this question.
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