What does this research mean for the field?

Prenatal diagnosis of critical left heart obstructive lesions significantly decreases postnatal morbidity, including hemodynamic compromise and organ dysfunction, and reduces surgical delays, despite having no significant impact on surgical mortality. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

April 1, 1998American Journal of Perinatology

Effect of Prenatal Diagnosis of Critical Left Heart Obstruction on Perinatal Morbidity and Mortality

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Why the study?

Does prenatal diagnosis reduce postnatal morbidity and mortality in newborns with critical left heart obstructive lesions?

Population

68 newborns with critical left heart obstructive (LHO) lesions seen between July 1993 and July 1996

Comparison

Prenatal diagnosis vs Postnatal diagnosis

Design

Cohort

Authors

REReenu S. EapenMedical City Children's Hospital DRDaniel RowlandMinistry of Defence WFWayne H. FranklinLoyola University Chicago

Discussion

Member takes

Implication

Supports prenatal diagnosis to reduce morbidity and delays in left heart obstruction; leaves open mortality benefit pending prospective trials.

Structured PICO

Does prenatal diagnosis reduce postnatal morbidity and mortality in newborns with critical left heart obstructive lesions?

Population

68 newborns with critical left heart obstructive (LHO) lesions seen between July 1993 and July 1996

Intervention

Prenatal diagnosis

Comparator

Postnatal diagnosis

Outcome

Postnatal morbidity and mortality (including degree of metabolic acidosis, hemodynamic instability, noncardiac organ dysfunction, delayed surgical intervention, and surgical mortality)hard clinical

Prenatal diagnosis of critical left heart obstruction improves perinatal morbidity and reduces surgical delays compared to postnatal diagnosis, although it does not significantly impact surgical mortality.

Cite This Study

Eapen et al. (1998) studied this question.

synapsesocial.com/papers/6a1e84c840bc8a3dd769023e https://doi.org/10.1055/s-2007-993934

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Implication

Supports prenatal diagnosis to reduce morbidity and delays in left heart obstruction; leaves open mortality benefit pending prospective trials.

Effect of Prenatal Diagnosis of Critical Left Heart Obstruction on Perinatal Morbidity and Mortality

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Effect of Prenatal Diagnosis of Critical Left Heart Obstruction on Perinatal Morbidity and Mortality

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider