Why the study?
Does the Valsalva maneuver elicit abnormal fMRI responses in central ANS regulatory areas in patients with heart failure compared to controls?
Does the Valsalva maneuver elicit abnormal fMRI responses in central ANS regulatory areas in patients with heart failure compared to controls?
Heart failure patients demonstrate altered central autonomic nervous system responses to the Valsalva maneuver on fMRI, suggesting potential targets for neuroprotective therapeutics.
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May highlight CNS targets for HF neuroprotection; hypothesis-generating and requires prospective validation before clinical consideration.
Woo et al. (2007) studied this question.
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