Why the study?
Does quinapril improve blood pressure and renal function in patients with essential hypertension and impaired renal function?
Population
8 patients with mild to moderate essential hypertension and mild impairment of renal function due to…
Comparison
Quinapril hydrochloride 5-10 mg/day for 12 weeks vs Baseline (before treatment)
Design
Case_series
Follow-up
12 weeks
Authors
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May support quinapril for BP and GFR in essential hypertension with mild impairment; leaves open confirmation in randomized trials.
Does quinapril improve blood pressure and renal function in patients with essential hypertension and impaired renal function?
Short-term quinapril administration significantly reduces blood pressure and improves renal function in patients with essential hypertension and mild renal impairment.
Owada et al. (1997) studied this question.
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