Why the study?
Does dopamine infusion alter left ventricular performance in anesthetized intact dogs?
Does dopamine infusion alter left ventricular performance in anesthetized intact dogs?
Dopamine increases myocardial contractility via direct myocardial action without significantly altering heart rate, systemic blood pressure, or preload in an intact dog model.
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Animal data on dopamine's inotropic effects should not change practice; leaves open human translation.
Black et al. (1966) studied this question.
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