What does this research mean for the field?

Q: What does this research mean for the field?

Antioxidant treatment with vitamins C and E prevents renal damage, improves renal hemodynamics, and reduces arterial pressure in salt-sensitive hypertension. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

April 19, 2005HypertensionOpen Access

Antioxidant Treatment Prevents Renal Damage and Dysfunction and Reduces Arterial Pressure in Salt-Sensitive Hypertension

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Why the study?

Does antioxidant treatment with vitamins C and E prevent renal damage and reduce arterial pressure in Dahl salt-sensitive rats on a high-sodium diet?

Structured PICO

Does antioxidant treatment with vitamins C and E prevent renal damage and reduce arterial pressure in Dahl salt-sensitive rats on a high-sodium diet?

Population

33 7- to 8-week old Dahl SS/Rapp strain rats

Intervention

Vitamin E (111 IU/d) in food and vitamin C (98 mg/d) in drinking water for 5 weeks

Comparator

No vitamin C and E supplementation

Outcome

Renal damage, glomerular filtration rate (GFR), renal plasma flow, and arterial pressuresurrogate

Discussion

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Implication

May support antioxidants in salt-sensitive rat models; leaves open human translation.

Cite This Study

Tian et al. (2005) studied this question.

synapsesocial.com/papers/6a1e9b5d544bdf605faf13fc https://doi.org/10.1161/01.hyp.0000160404.08866.5a

Topics

Hypertension management

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Antioxidant Treatment Prevents Renal Damage and Dysfunction and Reduces Arterial Pressure in Salt-Sensitive Hypertension

Structured PICO

Discussion

Implication

Cite This Study

Topics

Antioxidant Treatment Prevents Renal Damage and Dysfunction and Reduces Arterial Pressure in Salt-Sensitive Hypertension

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

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