Why the study?
Does the use of steroid-eluting ventricular pacing electrodes alter the histological tissue response compared to non-steroid-eluting electrodes in PM/ICD patients?
Does the use of steroid-eluting ventricular pacing electrodes alter the histological tissue response compared to non-steroid-eluting electrodes in PM/ICD patients?
Steroid-eluting ventricular pacing electrodes show only borderline histological differences compared to non-steroid-eluting electrodes, with slightly thinner fibrous sheaths but more frequent granulation tissue and foreign body reactions.
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Minimal histological differences should not alter electrode selection; leaves open need for outcome-focused studies.
Dvořák et al. (2011) studied this question.
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