Key result
Direct oral anticoagulant concentration monitoring can guide clinical decision-making in specific scenarios, highlighting the need for real-world studies on concentration-outcome associations.
Why the study?
Despite standard fixed-dose use of DOACs, monitoring is recommended in specific clinical scenarios, and clinicians need familiarity with laboratory assay sensitivities and DOAC concentration measurement to guide management.
Laboratory monitoring of DOAC concentrations may be necessary in specific clinical scenarios to guide appropriate clinical decision-making.
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Supports targeted DOAC monitoring in select scenarios; leaves open outcome associations pending real-world validation.
Patel et al. (2019) conducted a review in Anticoagulation therapy. Direct oral anticoagulants (DOACs) was evaluated. Direct oral anticoagulant concentration monitoring can guide clinical decision-making in specific scenarios, highlighting the need for real-world studies on concentration-outcome associations.
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