Key result
Simulations using a novel computational heart model demonstrated that external cardiac force patches can restore healthy blood flow and stroke work in a pathological heart model.
Why the study?
External cardiac assist devices are promising for treating heart failure but difficult to design, motivating computer-based optimization approaches.
Does external actuation with force patches restore healthy blood flow in a computational model of a pathological heart?
Population
Computational model of unsupported healthy and pathological hearts
Comparison
Exemplary external actuation versus unsupported pathological heart model
Design
Computational modeling framework study
Authors
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Does not support clinical use; leaves open computational models for guiding future device testing.
Does external actuation with force patches restore healthy blood flow in a computational model of a pathological heart?
A novel computational modeling framework successfully simulates cardiac electromechanics and hemodynamics, demonstrating that external force patches can theoretically restore healthy blood flow in a failing heart.
Kummer et al. (2022) studied Heart failure. External ventricular assist device (force patches) vs. Unsupported pathological heart model was evaluated on Restoration of healthy blood flow and stroke work. Simulations using a novel computational heart model demonstrated that external cardiac force patches can restore healthy blood flow and stroke work in a pathological heart model.
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