October 1, 1992Diabetes Care
Greater Effect of Glycemia on Incidence of Hypertension in Women Than in Men
Key result
Worsening glucose tolerance (NIDDM vs NGT) was associated with a higher relative risk of incident hypertension in women (RR 2.65) than in men (RR 1.61) over 8 years of follow-up.
Why the study?
Does abnormal glucose tolerance increase the incidence of hypertension more in women than in men?
Population
1,462 subjects from the San Antonio Heart Study, a population-based study of diabetes and cardiovascular…
Comparison
Abnormal glucose tolerance vs Normal glucose tolerance (NGT)
Design
Cohort
Follow-up
8 years
Authors
Discussion
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Member takes
Implication
May warrant sex-specific BP monitoring in diabetes; extends evidence on excess CHD risk in diabetic women.
Study Design
Type
Cohort (n=1,462)
Structured PICO
Does abnormal glucose tolerance increase the incidence of hypertension more in women than in men?
P
Population
1,462 men and women from the population-based San Antonio Heart Study, followed for 8 years to evaluate the effect of glycemia on the incidence of hypertension.
E
Exposure
Abnormal glucose tolerance (Non-insulin-dependent diabetes mellitus [NIDDM] and impaired glucose tolerance [IGT])
C
Comparator
Normal glucose tolerance (NGT)
O
Outcome
Incidence of hypertension
Main Result
Relative Risk: 2.65
Abnormal glucose tolerance confers a significantly higher relative risk of developing hypertension in women compared to men, which may partially explain the excess coronary heart disease risk in diabetic women.
Cite This Study
Haffner et al. (1992) conducted a cohort in Abnormal glucose tolerance (NIDDM and IGT) (n=1,462). Abnormal glucose tolerance (NIDDM and IGT) vs. Normal glucose tolerance (NGT) was evaluated on Incidence of hypertension (RR 2.65). Worsening glucose tolerance (NIDDM vs NGT) was associated with a higher relative risk of incident hypertension in women (RR 2.65) than in men (RR 1.61) over 8 years of follow-up.