Population
101 never-treated nondiabetic subjects with essential hypertension
Design
Cross-sectional
Authors
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Associations of IGF-1 and insulin with LV mass/geometry should not yet change practice; they leave open causal roles pending longitudinal confirmation.
Circulating insulin and IGF-1 are powerful independent determinants of left ventricular mass and geometry in untreated patients with essential hypertension and normal glucose tolerance.
Verdecchia et al. (1999) studied this question.
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