Population
Isolated hearts from rats with cardiac hypertrophy produced by banding the abdominal aorta for an 8-week…
Comparison
Low-flow ischemia after labeling the glycogen… vs Sham-operated control rat hearts
Design
Preclinical
Authors
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No difference in glycogen-derived glucose during ischemia in hypertrophied versus control hearts; leaves open relevance to human hypertrophy or targeted therapies.
Glycogen is a significant source of glucose during low-flow ischemia, but its contribution does not differ between hypertrophied and control rat hearts.
Schönekess et al. (1997) studied this question.
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