Why the study?
Does isolated AV block I have pathological significance in asymptomatic young men compared to healthy controls?
Does isolated AV block I have pathological significance in asymptomatic young men compared to healthy controls?
Isolated first-degree AV block in asymptomatic young men that normalizes with increased sympathetic tone likely has no pathological significance.
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Isolated first-degree AV block normalizing with sympathetic tone may lack pathological significance in asymptomatic young men; leaves open need for prospective outcome studies.
Twenty-nine young men with AV block I (P-R interval greater than 0.22 sec), without any history of heart disease, have been compared with 112 randomly selected healthy men of the same age. In 24 subjects who were free from concomitant ECG changes the P-R interval was normalized during orthostatic test and/or physical exercise. This group did not differ from the controls regarding anthropometric data and physical work capacity except for a higher heart rate at rest, thus suggesting that in these subjects an occurrence of AV block I has no pathological significance. However, it cannot be excluded that the block is a sequela, for instance, to myocarditis. Three subjects with AV block I and inverted T waves in the precordial leads and two subjects with unchanged P-R intervals to increased sympathetic tone had on average a smaller body size, a higher HR and systolic BP in recumbent position and smaller blood volumes.
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Ahlborg et al. (1977) studied this question.
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