September 30, 2005Lipids in Health and DiseaseOpen Access

Postprandial lipemia in men with metabolic syndrome, hypertensives and healthy subjects

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Why the study?

Does metabolic syndrome or hypertension alter postprandial lipemia after an oral fat tolerance test compared to healthy subjects?

Population

64 Greek men, including 33 with metabolic syndrome, 17 with hypertension, and 14 healthy subjects…

Comparison

Oral fat tolerance test consisting of a fatty… vs Comparison between three groups: men with…

Design

Cross-sectional

Follow-up

8 hours

Authors

GKGenovefa KolovouPreventive Cardiology KAKatherine K. AnagnostopoulouTechnological Educational Institute of Piraeus APAntonis N. PavlidisSt Thomas' Hospital

Discussion

Member takes

Implication

May warrant postprandial lipemia assessment in MetS; leaves open causal role of fasting triglycerides in prospective studies.

Structured PICO

Does metabolic syndrome or hypertension alter postprandial lipemia after an oral fat tolerance test compared to healthy subjects?

Population

64 Greek men, including 33 with metabolic syndrome (MetS, defined by ATP III criteria), 17 with hypertension (HTN), and 14 healthy subjects. Exclusions: heavy drinking, liver and renal disease, hypothyroidism, professional sport activity, and the use of hypolipidemic drugs.

Intervention

Oral fat tolerance test (OFTT) consisting of a fatty meal (83.5% fat, 14.0% carbohydrates, 2.5% proteins) consumed within 20 minutes, dosed based on body surface area (350 g for 2 m2).

Comparator

Comparison between three groups: men with metabolic syndrome, hypertensive men, and healthy men.

Outcome

Postprandial triglyceride (TG) response quantified using the area under the curve (AUC) for TG measured before and at 4, 6, and 8 hours after the oral fat tolerance test.surrogate

Fasting triglyceride concentration is the main determinant of postprandial lipemia, which is significantly exaggerated in men with metabolic syndrome compared to hypertensive and healthy subjects.

Cite This Study

Kolovou et al. (2005) studied this question.

synapsesocial.com/papers/6a1efdbd08df8bb755b3066f https://doi.org/10.1186/1476-511x-4-21

Topics

Hypertension management

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Postprandial lipemia in men with metabolic syndrome, hypertensives and healthy subjects

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Postprandial lipemia in men with metabolic syndrome, hypertensives and healthy subjects

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider