Key result
A 60-year-old male without typical risk factors developed an embolic stroke from a left ventricular thrombus, leading to a diagnosis of multiple myeloma as the likely underlying hypercoagulable cause.
Case Report (n=1)
No
This case highlights the importance of considering rare etiologies, such as malignancy (multiple myeloma), in patients presenting with left ventricular thrombus and embolic stroke without typical risk factors.
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May warrant considering occult malignancy in unexplained LV thrombus; hypothesis-generating case report requiring validation.
Left ventricular thrombi are most commonly observed in patients after a myocardial infarction with left ventricular aneurysm. We present a case of a 60 year old male who developed an embolic cerebrovascular accident (CVA) secondary to a left ventricular thrombus without evidence of an anteroapical aneurysm or diagnosed myocardial infarction. Outpatient investigation after hospitalization for the acute CVA led to an eventual diagnosis of multiple myeloma. This case reinforces the importance of considering rare etiologies including malignancy in patients who present without typical risk factors for embolic disease.
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Tennant et al. (2021) conducted a case report in Left ventricular thrombus and embolic stroke (n=1). Multiple myeloma was evaluated. A 60-year-old male without typical risk factors developed an embolic stroke from a left ventricular thrombus, leading to a diagnosis of multiple myeloma as the likely underlying hypercoagulable cause.
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