Key result
A 1-point increase in ideal cardiovascular health score was associated with a 0.128 mm decrease in carotid intima-media thickness and a 32% lower odds of having high cIMT (OR 0.68).
Why the study?
Ideal cardiovascular health is associated with lower cardiovascular disease risk, but its association with carotid intima-media thickness in young adults needed investigation.
Does ideal cardiovascular health reduce carotid intima-media thickness in young adults?
Cross-Sectional (n=1,295)
No
Does ideal cardiovascular health reduce carotid intima-media thickness in young adults?
Odds Ratio: 0.68 (95% CI 0.56–0.82)
p-value: p=<0.001
Higher ideal cardiovascular health scores are inversely associated with carotid intima-media thickness in young adults, highlighting the importance of health promotion strategies to prevent subclinical atherosclerosis.
Supports CVH promotion to limit early atherosclerosis in youth; hypothesis-generating, needs longitudinal confirmation before practice change.
Ideal cardiovascular health (CVH) is associated with a lower risk of developing cardiovascular diseases. This study aims to investigate the association of CVH metrics with carotid intima-media thickness (cIMT) as a marker of subclinical atherosclerosis in young adults. A cross-sectional study was performed on 1295 adults, average age of 29.7 ± 4.0 years, selected among the participants of the Tehran Lipid and Glucose Study (TLGS). The participants were divided into two CVH groups: Ideal CVH and poor/intermediate CVH. Multivariate-adjusted linear regression was used to determine the association of ideal CVH score with cIMT. Multivariate-adjusted odd ratios (ORs) were calculated for high cIMT (≥95%percentile). Also, the independent effects of each ideal CVH metric on cIMT were analyzed. The prevalence of ideal CVH was 9.3% in the studied population, and the mean of cIMT was 0.55±0.09 mm. A 1-point increase in CVH score was associated with a decrease of 0.128 mm (Beta [SE] = -0.128 [0. 002], p<0.001) in cIMT and rendered an odd ratio of 0.68 (OR = 0.68 [95% CI: 0.56-0.82], p<0.001) for having a high CIMT (≥95%percentile). Each ideal glucose, ideal blood pressure and ideal body mass index (BMI) had a significant inverse association with cIMT. There was a graded inverse association between ideal CVH score and cIMT among young adults, indicating that ideal CVH metrics are associated with better vascular health in this population. The low prevalence of ideal CVH highlighted the importance of implementing health promotion strategies.
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Chavoshi et al. (2021) conducted a cross-sectional in Subclinical atherosclerosis (n=1,295). Ideal cardiovascular health (CVH) score vs. Poor/intermediate CVH score was evaluated on High carotid intima-media thickness (cIMT ≥ 95% percentile) per 1-point increase in CVH score (OR 0.68, 95% CI 0.56-0.82, p=<0.001). A 1-point increase in ideal cardiovascular health score was associated with a 0.128 mm decrease in carotid intima-media thickness and a 32% lower odds of having high cIMT (OR 0.68).
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