Key result
Having 5-6 ideal cardiovascular health metrics was associated with a significantly lower risk of developing carotid plaques compared to 0-1 metrics (OR 0.46; 95% CI 0.27-0.79).
Why the study?
Ideal cardiovascular health predicts lower cardiovascular disease risk, but its prospective association with subclinical atherosclerosis in middle-aged and older Chinese adults required investigation.
Does a higher number of ideal cardiovascular health metrics prevent the development of subclinical atherosclerosis in middle-aged and elderly Chinese adults?
Population
8,395 Chinese adults aged ⪦ 40 years at baseline and 4,879 at follow-up
Comparison
Higher vs lower numbers of ideal CVH metrics
Design
Cross-sectional and prospective cohort analysis
Follow-up
4.3 years
Authors
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May support CVH optimization to limit subclinical atherosclerosis; leaves open causality and need for RCTs before practice change.
Cohort (n=8,395)
Does a higher number of ideal cardiovascular health metrics prevent the development of subclinical atherosclerosis in middle-aged and elderly Chinese adults?
Odds Ratio: 0.46 (95% CI 0.27–0.79)
A higher number of ideal cardiovascular health metrics is inversely associated with the development of subclinical atherosclerosis, though this effect is attenuated in older adults and men.
Wang et al. (2019) conducted a cohort in Subclinical atherosclerosis (n=8,395). 5-6 ideal cardiovascular health metrics vs. 0-1 ideal cardiovascular health metrics was evaluated on Developing carotid plaques (OR 0.46, 95% CI 0.27-0.79). Having 5-6 ideal cardiovascular health metrics was associated with a significantly lower risk of developing carotid plaques compared to 0-1 metrics (OR 0.46; 95% CI 0.27-0.79).
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