February 1, 2000AJP Heart and Circulatory Physiology

Muscle metaboreflex control of cardiac output and peripheral vasoconstriction exhibit different latencies

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Population

7 dogs performing steady-state treadmill exercise of mild and moderate workloads

Design

Preclinical

Authors

RARobert A. AugustyniakLincoln Memorial University EAEric J. AnsorgeWayne State University DODonal S. O’LearyWayne State University

Discussion

Member takes

Implication

Hypothesis-generating for metaboreflex timing in ischemia; leaves open translation to human exercise physiology.

Structured PICO

Population

7 dogs performing steady-state treadmill exercise of mild and moderate workloads (3.2 km/h at 0% grade and 6.4 km/h at 10% grade)

Intervention

Total vascular occlusion of hindlimb blood flow

Outcome

Mechanisms mediating metaboreflex-induced increases in systemic arterial pressure and their differential latencies (cardiac output vs. peripheral vasoconstriction)surrogate

The initial metaboreflex-mediated pressor response to hindlimb vascular occlusion during exercise in dogs is primarily driven by peripheral vasoconstriction rather than increased cardiac output.

Cite This Study

Augustyniak et al. (2000) studied this question.

synapsesocial.com/papers/6a1f1ae6e800cc4eef5529cd https://doi.org/10.1152/ajpheart.2000.278.2.h530

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Muscle metaboreflex control of cardiac output and peripheral vasoconstriction exhibit different latencies

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Muscle metaboreflex control of cardiac output and peripheral vasoconstriction exhibit different latencies

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider