Key result
Both low and high blood pressure were associated with an excess risk of death compared to medium blood pressure in men aged 40-69 years, demonstrating a U-shaped relationship over 13 years.
Why the study?
Is mortality a U-shaped function of blood pressure in middle-aged men?
Cohort (n=954)
Is mortality a U-shaped function of blood pressure in middle-aged men?
Both high and low blood pressures are associated with increased mortality in middle-aged men, suggesting a U-shaped risk curve.
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Supports U-shaped BP-mortality link in middle-aged men; leaves open causality and need for prospective trials before changing targets.
Lindholm et al. (1985) reported a cohort. Low and high blood pressure vs. Medium blood pressure was evaluated on Mortality. Both low and high blood pressure were associated with an excess risk of death compared to medium blood pressure in men aged 40-69 years, demonstrating a U-shaped relationship over 13 years.
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