Key result
Vagotomy and atropine increased coronary flow and heart rate but decreased left ventricular efficiency in dogs, whereas chronic sympathectomy decreased flow and increased efficiency.
Authors
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No immediate clinical application from canine data; leaves open human translation of autonomic effects on efficiency.
Scott et al. (1959) studied this question. Vagotomy, atropine, and sympathectomy vs. Baseline was evaluated on Coronary blood flow. Vagotomy and atropine increased coronary flow and heart rate but decreased left ventricular efficiency in dogs, whereas chronic sympathectomy decreased flow and increased efficiency.
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