What are the differences in muscle fiber parameters between normal volunteers and patients with myotonia congenita?
The study measured various electrophysiological and biochemical parameters in isolated intercostal muscle fibers of normal volunteers and patients with myotonia congenita.
A B S T R A C T In isolated fiber bundles of external intercostal muscle from each of 13 normal volunteers and each of 6 patients with myotonia congenita, some or all of the following were measured: concentrations of Na+, K+, and Cl-, extracellular volume, water content, K+ efflux, fiber size, fiber cable parameters, and fiber resting potentials.
Lipicky et al. (1971) studied this question.