Key result
Sleep deprivation is associated with cardiovascular risk factors that aggravate the pathogenesis and outcomes of coronary heart disease.
Why the study?
Does sleep deprivation increase morbidity and mortality in patients with coronary heart disease?
Does sleep deprivation increase morbidity and mortality in patients with coronary heart disease?
Sleep deprivation is associated with multiple cardiovascular risk factors and aggravates the pathogenesis and outcomes of coronary heart disease.
May warrant sleep assessment in CHD patients; leaves open whether interventions improve outcomes.
Sleep deprivation (SD) has been associated with an increased morbidity and mortality of coronary heart disease (CHD). SD could induce autonomic nervous dysfunction, hypertension, arrhythmia, hormonal dysregulation, oxidative stress, endothelial dysfunction, inflammation and metabolic disorder in CHD patients. This paper reviewed the study results of SD in clinical trials and animal experiments and concluded that SD was associated with cardiovascular risk factors, which aggravated CHD in pathogenesis and outcomes.
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Yuan et al. (2016) conducted a review in Coronary Heart Disease. Sleep deprivation was evaluated. Sleep deprivation is associated with cardiovascular risk factors that aggravate the pathogenesis and outcomes of coronary heart disease.
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