Key result
Higher cardiometabolic index is linked to ~29% greater CKD risk in older hypertensive adults.
Why the study?
Literature on the association between the cardiometabolic index and chronic kidney disease risk is limited, especially in hypertensive populations.
Cross-Sectional (n=13,717)
No
Answers are grounded in this paper and cite their sources.
The cardiometabolic index is independently associated with an increased risk of chronic kidney disease in older (≥65 years) but not younger adults with hypertension.
Literature on the association between the cardiometabolic index (CMI) and chronic kidney disease (CKD) risk is limited, especially in hypertensive populations. The objective of the present investigation was to assess the relationship between the CMI and CKD risk in a hypertensive population. The current cross‐sectional study included a total of 13 717 individuals with hypertension. The calculation of the CMI was based on the waist‐to‐height ratio and the triglyceride‐to‐high‐density lipoprotein cholesterol ratio. The definition of CKD was based on an estimated glomerular filtration rate (eGFR) of less than 60 mL/min/1.73 m 2 . The prevalence of CKD was found to be 4.24% in younger adults (aged < 65 years) and 14.93% in the elderly (aged ≥ 65 years). The results of the multivariate regression analysis indicated that in the elderly group, the CMI was positively associated with CKD risk (odd ratio [OR] 1.29; 95% confidence interval [CI]: 1.14, 1.46), while no significant relationship was observed in the younger group (OR 1.04, 95% CI: 0.85, 1.27). Furthermore, subgroup analyses did not identify any potential factors that could modify the relationship between the CMI and CKD risk (all p for interaction > 0.05). Among adults with hypertension, there was an independent and positive correlation between the CMI and CKD risk in the elderly, whereas such a correlation was not observed in younger adults. Trial Registration : ClinicalTrials.
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Yu et al. (2024) conducted a cross-sectional in Hypertension (n=13,717). Cardiometabolic index (CMI) vs. Lower CMI levels was evaluated on Chronic kidney disease (eGFR < 60 mL/min/1.73 m2) (OR 1.29, 95% CI 1.14, 1.46, p=< 0.001). In adults with hypertension aged 65 years or older, a higher cardiometabolic index was independently associated with an increased risk of chronic kidney disease.
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