Stereodivergent Synthesis of Allylic Phosphonates

Key Points

• The aim is to establish a method for the stereodivergent synthesis of allylic phosphonates.
• Developed a transition-metal-free synthesis method under mild conditions.
• Utilized readily available dialkyl phosphites, vinyltriphenylphosphonium chloride, and aldehydes.
• Produced various cis- and trans-allylic phosphonates on demand.
• Achieved good to excellent stereoselectivities in the synthesis of allylic phosphonates.
• Successfully produced an array of cis- and trans-allylic phosphonates.
• Yielded a significant amount of the desired products under mild conditions.

Abstract