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June 3, 2026BMJ Case Reports0 citations

Dramatic onset and resolution of Leser-Trélat sign

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IYIsabel YoonEKEllen Kim

Key Points

  • To describe the dramatic onset and resolution of Leser-Trélat sign in an 80-year-old man presenting with a rash.
  • Patient evaluation included physical examination and documentation of rash characteristics over 4 months.
  • Patient exhibited exfoliative erythroderma, palmoplantar keratoderma, and numerous brown papules upon examination.

Abstract

A man in his 80s presented with a new-onset rash that had begun 4 months prior. On physical exam, he was found to have exfoliative erythroderma and palmoplantar keratoderma. In addition, numerous brown papules were scattered across the back, which the patient reported had erupted concurrently with

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Cite This Study

Yoon et al. (2026) studied this question.

synapsesocial.com/papers/6a1fc56bdee9eb8c0dce6d97https://doi.org/10.1136/bcr-2025-270056
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Sign of Leser-Trelat in Colorectal Adenocarcinoma2010 · 14 citations
  2. 2Transient eruptive seborrheic keratoses associated with erythrodermic psoriasis and erythrodermic drug eruption: Report of two cases2001 · 33 citations
  3. 3Eruptive Seborrheic Keratoses Are Associated With a Co-Occurring Malignancy in the Majority of Reported Cases: A Systematic Review2021 · 7 citations
  4. 4Paraneoplastic cutaneous manifestations: concepts and updates*2013 · 193 citations
  5. 5Leser‐Trélat Sign Associated with Sézary Syndrome1995 · 24 citations