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This study aims to evaluate the impact of timing on autologous breast reconstruction in patients receiving postmastectomy radiation therapy.

June 3, 2026Open Access

"Immediate versus delayed autologous breast reconstruction in patients undergoing post-mastectomy radiation therapy: A paradigm shift"

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This study aims to evaluate the impact of timing on autologous breast reconstruction in patients receiving postmastectomy radiation therapy.
Retrospective chart review of patients undergoing PMRT and autologous breast reconstruction.
Comparison of complication and revision rates between immediate and delayed breast reconstructions.
Inclusion of 36 patients in the immediate reconstruction group and 89 in the delayed group.
Overall complication rates were comparable; however, the IBR group had significantly lower revision rates (p = 0.02).
DBR required more fat grafting and contralateral mastopexies (p = 0.01 and p = 0.02, respectively).
No significant differences observed in fat necrosis excision or need for secondary flap reconstruction.

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Retrospective chart review compares outcomes in immediate and delayed reconstruction in PMRT patients, suggesting IBR offers fewer revisions.

Young et al. (2022) studied this question.

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Retrospective chart review compares outcomes in immediate and delayed reconstruction in PMRT patients, suggesting IBR offers fewer revisions.