What question did this study set out to answer?

The study aims to evaluate the effectiveness of sodium hypochlorite and hyaluronic acid as adjuncts to subgingival re-instrumentation.

June 3, 2026Open Access

Effect of sodium hypochlorite and hyaluronic acid in subgingival re-instrumentation - a randomized clinical trial.

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Authors

GJGert JungbauerUniversity of Bern FSFabienne StalderUniversity of Bern SMSteffen Müller

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Implication

Randomized trial investigates clinical and microbiological benefits of sodium hypochlorite and hyaluronic acid in subgingival re-instrumentation, suggesting better outcomes.

Key Points

The study aims to evaluate the effectiveness of sodium hypochlorite and hyaluronic acid as adjuncts to subgingival re-instrumentation.
42 patients received either control SRI or adjunctive AA-NaOCl and xHA.
Clinical periodontal parameters, immunological biomarkers, and periopathobionts were evaluated at baseline, 3, and 6 months.
IL-1β and MMP-8 levels were measured using ELISA; periopathobionts were quantified by qPCR.
Test group showed an additional PD reduction of 0.50 mm (p = 0.008) and CAL gain of 0.57 mm (p = 0.017) compared to control.
Residual pockets decreased by 88.1% in the test group and 38.1% in the control group.
Five periopathobionts significantly decreased in the test group.

Cite This Study

Jungbauer et al. (2026) studied this question.

synapsesocial.com/papers/6a1fc7dcdee9eb8c0dce8741 https://doi.org/10.48620/98292

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Implication

Randomized trial investigates clinical and microbiological benefits of sodium hypochlorite and hyaluronic acid in subgingival re-instrumentation, suggesting better outcomes.

Effect of sodium hypochlorite and hyaluronic acid in subgingival re-instrumentation - a randomized clinical trial.

Discussion

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Implication

Key Points

Cite This Study

Effect of sodium hypochlorite and hyaluronic acid in subgingival re-instrumentation - a randomized clinical trial.

Discussion

Member takes

Implication

Key Points

Cite This Study

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