Key result
A survey of European anaesthetists revealed significant national differences in the use of muscle relaxants and reversal agents, with French anaesthetists using less succinylcholine and reversal agents than their British and German peers.
Why the study?
What are the national differences in the peri-operative use of muscle relaxants and their reversal agents among anaesthetists in France, Germany, and Great Britain?
Cross-Sectional
Yes
What are the national differences in the peri-operative use of muscle relaxants and their reversal agents among anaesthetists in France, Germany, and Great Britain?
There are significant national differences in the peri-operative use of muscle relaxants and reversal agents among anaesthetists in France, Germany, and Great Britain.
Answers are grounded in this paper and cite their sources.
National differences in relaxant use highlight practice variation; leaves open whether harmonization affects safety or outcomes.
A survey was conducted among British, French and German anaesthetists to evaluate possible national differences in the peri-operative use of muscle relaxants and their reversal agents. The same non-depolarizing relaxants are used in all three countries, with the exception of d-tubocurarine, which is only available in Great Britain, and alcuronium which is mainly used in Germany. The French anaesthetists seem to use significantly less succinylcholine than their peers in Great Britain or Germany for both elective and emergency intubation. Monitoring of neuromuscular blockade still relies mainly on "clinical judgement'. Reversal of non-depolarizing muscle relaxants is performed routinely in Great Britain, while a substantial number of French anaesthetists avoid the use of a reversal. Dose regimes for neostigmine vary largely, with German anaesthetists administering the lowest, and British anaesthetists administering the highest doses. Side effects of reversal agents are reported by colleagues from all three countries in too high a percentage to justify uncritical administration of these drugs. In Germany there seems to be a noteworthy lack of recovery facilities.
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Osmer et al. (1996) conducted a cross-sectional in Peri-operative use of muscle relaxants and reversal agents. National practices in peri-operative use of muscle relaxants and reversal agents vs. Differences between France, Germany, and Great Britain was evaluated on Differences in the peri-operative use of muscle relaxants and their reversal agents. A survey of European anaesthetists revealed significant national differences in the use of muscle relaxants and reversal agents, with French anaesthetists using less succinylcholine and reversal agents than their British and German peers.
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