Population
Global population affected by poliomyelitis
Comparison
Poliovirus vaccines vs Prevaccine era
Design
Review
Key result
Global expansion of polio immunization reduced annual paralytic disease from an estimated prevaccine level of at least 600,000 cases to fewer than 1,000 cases in 2000.
Authors
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Supports sustained immunization programs; leaves open full eradication feasibility.
Poliovirus vaccines have dramatically reduced global paralytic poliomyelitis cases from over 600,000 annually to fewer than 1,000, though challenges to final eradication remain.
Nathanson et al. (2010) conducted a review in Poliomyelitis. Poliovirus vaccines vs. Prevaccine era was evaluated on Annual paralytic disease cases. Global expansion of polio immunization reduced annual paralytic disease from an estimated prevaccine level of at least 600,000 cases to fewer than 1,000 cases in 2000.