Key result
The Global Polio Eradication Initiative has greatly diminished worldwide cases, but the genetic instability of the oral polio vaccine poses challenges due to circulating vaccine-derived polioviruses.
A review of the history, molecular biology, and eradication efforts of poliomyelitis.
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Warrants ongoing surveillance for vaccine-derived strains; leaves open optimal vaccine strategies for eradication.
Nidia H De Jesus (2007) conducted a review in Poliomyelitis. Poliovirus vaccines (OPV and IPV) was evaluated. The Global Polio Eradication Initiative has greatly diminished worldwide cases, but the genetic instability of the oral polio vaccine poses challenges due to circulating vaccine-derived polioviruses.
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