What does this research mean for the field?

The final stages of the polio eradication program are particularly challenging due to the silent nature of the infection and the ability of the oral polio vaccine (OPV) to evolve in recipients, necessitating a deep understanding of the virus's pathogenesis and virology. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

December 1, 2011Journal of General VirologyOpen Access

The polio-eradication programme and issues of the end game

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Population

Humans (general population regarding polio vaccination)

Design

Review

Authors

PMPhilip D. MinorUniversity of Essex

Discussion

Member takes

Implication

Silent transmission and OPV evolution sustain eradication barriers; leaves open optimized vaccine and surveillance strategies.

Structured PICO

Population

Humans (general population regarding polio vaccination)

Intervention

Polio vaccination (oral polio vaccine [OPV] and inactivated polio vaccine [IPV])

Outcome

Polio eradication

Understanding the pathogenesis and virology of poliovirus, including the evolution of OPV, is crucial for the success of the global polio eradication programme.

Cite This Study

Philip D. Minor (2011) studied this question.

synapsesocial.com/papers/6a1e79b740bc8a3dd768f1f7 https://doi.org/10.1099/vir.0.036988-0

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The polio-eradication programme and issues of the end game

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The polio-eradication programme and issues of the end game

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider