Carotid Intima-Media Thickness and Plaque Characteristics as a Risk Factor for Stroke in Japanese Elderly Men
Why the study?
Does increased carotid intima-media thickness and the presence of uncalcified plaque increase the risk of stroke in elderly Japanese men without previous cardiovascular disease?
Population
1,289 Japanese men aged 60 to 74 years without a previous stroke or coronary heart disease
Comparison
Increased carotid intima-media thickness and… vs Lowest quartile of maximum IMT of the common…
Design
Cohort
Follow-up
4.5 years
Authors
Discussion
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Member takes
Implication
Carotid IMT was associated with higher stroke risk in elderly Japanese men; leaves open utility for risk stratification beyond standard factors.
Structured PICO
Does increased carotid intima-media thickness and the presence of uncalcified plaque increase the risk of stroke in elderly Japanese men without previous cardiovascular disease?
P
Population
1,289 Japanese men aged 60 to 74 years without a previous stroke or coronary heart disease
I
Intervention
Increased carotid intima-media thickness (highest quartile of maximum IMT of the common carotid artery ≥1.07 mm) and presence of uncalcified plaque in the internal carotid artery assessed by ultrasonography
C
Comparator
Lowest quartile of maximum IMT of the common carotid artery (≤0.77 mm) and absence of plaque
O
Outcome
Incidence of strokehard clinical
Increased common carotid artery intima-media thickness and the presence of uncalcified plaque in the internal carotid artery are significant predictors of stroke in elderly Japanese men.
Cite This Study
Kitamura et al. (2004) studied this question.