Key result
Patients with type 2 diabetes mellitus had significantly higher median serum betatrophin levels compared to healthy controls (20 vs 18 ng/l; P<0.001).
Why the study?
To evaluate serum betatrophin levels in healthy individuals and patients with type 2 diabetes mellitus, and to investigate its association with insulin resistance and other metabolic parameters.
Are serum betatrophin levels elevated in patients with type 2 diabetes mellitus compared to healthy controls?
Comparison
Patients with T2DM vs healthy control subjects
Design
Case-control study
Authors
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Elevated betatrophin was associated with T2DM; hypothesis-generating for biomarker utility, needs prospective validation.
Case-Control (n=89)
Are serum betatrophin levels elevated in patients with type 2 diabetes mellitus compared to healthy controls?
Absolute Event Rate: 20% vs 18%
p-value: p=<0.001
Serum betatrophin levels are significantly elevated in patients with type 2 diabetes and may serve as a potential biomarker for the disease.
Abbas et al. (2022) conducted a case-control in Type 2 diabetes mellitus (n=89). Type 2 diabetes mellitus vs. Healthy controls was evaluated on Serum betatrophin level (p=<0.001). Patients with type 2 diabetes mellitus had significantly higher median serum betatrophin levels compared to healthy controls (20 vs 18 ng/l; P<0.001).
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