Role of Omega-6 Fatty Acid Metabolism in Cardiac Surgery Postoperative Bleeding Risk

Figures

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  Figure 1.. Platelet count (A), variability in percentage (B), platelet mean volume (C), and platelet distribution width (D) of preoperative and 6- and 24-hr postoperative patients. Values are presented in median with interquartile range.

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  Figure 2.. A, Correlation of postoperative bleeding (mL) within the first postoperative 12 hr and preoperative quantification of arachidonic acid. B, Preoperative arachidonic acid levels between patients with (green) or without (red) a significant postoperative bleeding (defined by postoperative chest tube blood loss of more than 600 mL within 12 hr). C, Median postoperative chest tube blood within 12 hr according to arachidonic acid quantification.

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  Figure 3.. A, Postoperative transfusion rate considering preoperative arachidonic acid quantification and the reduction in percentage at postoperative 6 hr. B, Receiver operating characteristic curve based on the preoperative arachidonic acid measurements and represented by an area under the curve (AUC) of 0.73 indicating a satisfactory predictive ability. C, Correlation between human interleukin 6 levels and variability in arachidonic acid levels at 6 hr postoperative (percent change compared with preoperative levels).