The opposing actions of apoC-III and apoE on VLDL and LDL subspecies establish the basic structure of human apoB lipoprotein metabolism in normolipidemia and hypertriglyceridemia.
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Clarifies apoB lipoprotein dynamics in hypertriglyceridemia; leaves open whether apoC-III inhibition improves outcomes beyond TG reduction.
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Frank M. Sacks (2014) studied this question.
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