Why the study?
Does Glanzmann thrombasthenia protect against the development of atherosclerosis?
Does Glanzmann thrombasthenia protect against the development of atherosclerosis?
Patients with Glanzmann thrombasthenia lacking specific platelet glycoprotein receptors are not protected from developing early atherosclerosis, challenging the hypothesis that these platelets are essential for early atherogenesis.
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Glanzmann thrombasthenia does not protect against early atherosclerosis; challenges receptor-essential hypothesis but remains hypothesis-generating.
Shpilberg et al. (2002) studied this question.
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