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This review discusses the pathophysiology of pregnancy-associated venous thromboembolism, the role of thrombophilia, and strategies for identifying high-risk women and preventing venous thrombosis.
This review discusses the pathophysiology of pregnancy-associated venous thromboembolism, the role of thrombophilia, and strategies for risk identification and prevention.
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May inform VTE risk assessment in pregnancy; leaves open optimal thrombophilia-guided prevention strategies.
Pregnancy-associated venous thromboembolism continues to be a significant cause of maternal mortality and morbidity. Unfortunately, many of these deaths could be prevented by optimal prophylaxis and management. This review describes recent developments in the understanding of the pathophysiology of the disease processes and the contribution that thrombophilia makes. Potential strategies for identification of women at high risk and current and future therapeutic strategies for the prevention of venous thrombosis in pregnancy are also discussed.
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Nelson et al. (2007) conducted a review in Pregnancy-associated venous thromboembolism. Prophylaxis and management strategies was evaluated. This review discusses the pathophysiology of pregnancy-associated venous thromboembolism, the role of thrombophilia, and strategies for identifying high-risk women and preventing venous thrombosis.
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