Why the study?
Pulmonary embolism remains the leading cause of maternal mortality despite heparin use, yet evidence on optimal thromboprophylaxis in pregnancy is scarce.
What is the current evidence on optimal thromboprophylaxis with heparin for preventing VTE and recurrent pregnancy complications in pregnant women?
What is the current evidence on optimal thromboprophylaxis with heparin for preventing VTE and recurrent pregnancy complications in pregnant women?
This review summarizes the current evidence regarding the use of heparin for thromboprophylaxis to prevent VTE and pregnancy complications in high-risk pregnant women.
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Insufficient evidence on thromboprophylaxis in pregnancy persists; leaves optimal strategies for high-risk cases open to prospective trials.
Middeldorp et al. (2022) studied this question.
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