August 1, 1993HeartOpen Access

Transient rise in serum interleukin-8 concentration during acute myocardial infarction.

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Why the study?

Does serum IL-8 concentration rise during acute myocardial infarction compared to stable angina or normal controls?

Population

5 consecutive patients with acute Q-wave myocardial infarction, 2 patients with stable angina who underwent…

Design

Cohort

Follow-up

36-72 hours

Authors

YAYasuaki AbeYamagata University MKMasanobu KawakamiJichi Medical University MKManabu KurokiYokohama National University

Discussion

Member takes

Implication

Transient IL-8 rise in early AMI is hypothesis-generating; leaves open its role in neutrophil injury and any clinical utility.

Structured PICO

Does serum IL-8 concentration rise during acute myocardial infarction compared to stable angina or normal controls?

Population

5 consecutive patients with acute Q-wave myocardial infarction, 2 patients with stable angina who underwent elective percutaneous transluminal coronary angioplasty, and 10 normal controls (total n=17).

Comparator

Patients with stable angina and normal controls

Outcome

Serum IL-8 concentration measured by enzyme linked immunosorbent assay (ELISA) over time (every four, eight or 12 hours for 36-72 hours)surrogate

Serum IL-8 concentration shows a transient rise during the very early phase of acute myocardial infarction, suggesting its potential role in neutrophil-mediated myocardial injury.

Cite This Study

Abe et al. (1993) studied this question.

synapsesocial.com/papers/6a1ff3c235281a23f90daf29 https://doi.org/10.1136/hrt.70.2.132

View Full Paper

Ask AI

Bookmark

Transient rise in serum interleukin-8 concentration during acute myocardial infarction.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Transient rise in serum interleukin-8 concentration during acute myocardial infarction.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider