Key result
Sex and weight were significant determinants in all the echocardiographic parameters studied to establish reference ranges in 609 healthy Dutch subjects.
Cross-Sectional (n=609)
This study establishes reference ranges for standard echocardiographic measurements in a healthy Dutch population, highlighting sex and weight as key determinants.
Supports sex- and weight-specific echocardiographic reference ranges in Dutch adults; leaves generalizability to other populations open.
Reference ranges for echocardiographic measurements were determined in 609 healthy Dutch subjects, using height, weight, age, sex, RR-interval and blood pressure (in adults only) as determinants. End-systolic as well as end-diastolic measurements of the aortic root as well as left ventricular inner diameter, posterior and septal thickness were taken, as was the left atrial end-systolic diameter. Multiple linear regression was performed of the form: M = A.(age)B.(height)C.(weight)D.(RR-interval)E.(sex)F. The residuals were calculated in order to determine the percentile limits by means of linear interpolation. Sex and weight were significant determinants in all the echocardiographic parameters studied. The results were presented twofold, with a simple version for males and females separately, using only weight as a determinant and allowing graphical presentation, and secondly a complex version taking into account all determinants, which can only be solved with help of a calculator.
No takes yet. Share an insight, caveat, or question.
Voogd et al. (1984) conducted a cross-sectional in Healthy (n=609). Determinants (height, weight, age, sex, RR-interval, blood pressure) was evaluated on Reference ranges for echocardiographic measurements. Sex and weight were significant determinants in all the echocardiographic parameters studied to establish reference ranges in 609 healthy Dutch subjects.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: