Key result
Immobilization of rat hindlimbs at less than resting length caused exponential decay in muscle weight and proteins with a half-time of 4-6 days, whereas stretching delayed atrophy.
Authors
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May inform muscle-length considerations during immobilization; leaves open translation to human disuse atrophy prevention.
Frank W. Booth (1977) studied Muscular atrophy. Immobilization of hindlimbs in plaster casts was evaluated on Time course for atrophy of muscle and selected proteins. Immobilization of rat hindlimbs at less than resting length caused exponential decay in muscle weight and proteins with a half-time of 4-6 days, whereas stretching delayed atrophy.
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