Key result
A high protein diet in rats increased plasma renin activity (10.0 vs 3.5 ng ANG I/ml/h, P<0.02) and decreased pressor responsiveness to angiotensin II.
Authors
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High-protein diets may alter renin-angiotensin responses in rats; hypothesis-generating and leaves open human translation.
Absolute Event Rate: 10% vs 3.5%
p-value: p=<0.02
Paller et al. (1986) studied this question. High protein diet vs. Low protein diet (6%) was evaluated on Plasma renin activity (PRA) (p=<0.02). A high protein diet in rats increased plasma renin activity (10.0 vs 3.5 ng ANG I/ml/h, P<0.02) and decreased pressor responsiveness to angiotensin II.
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