Why the study?
Does a low-protein diet increase renal renin and ACE mRNA expression in intact rats?
Population
Intact rats
Comparison
Low-protein (LP) feeding (6%) vs Normal protein diet
Design
Preclinical
Authors
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May explain diet-related renal changes in rats; leaves open human relevance and need for clinical studies.
Does a low-protein diet increase renal renin and ACE mRNA expression in intact rats?
A low-protein diet increases the expression of renal renin and ACE mRNA in intact rats, which may explain the associated renal hemodynamic changes.
Martinez-Maldonado et al. (1993) studied this question.
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