Why the study?
Does a high protein diet affect renal growth, hemodynamics, and intrarenal renin distribution in developing male Wistar rats?
Population
Male Wistar rats (n=24)
Comparison
40% protein diet from weaning until 6 or 12… vs 20% protein diet from weaning until 6 or 12…
Design
Preclinical
Follow-up
Until 6 or 12 weeks of age
Authors
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Does not guide human dietary practice; extends proximal renin distribution data in developing rat models.
Does a high protein diet affect renal growth, hemodynamics, and intrarenal renin distribution in developing male Wistar rats?
High protein feeding during development increases renal growth and glomerular filtration rate, and extends the intrarenal distribution of renin and its mRNA proximally along afferent arterioles in rats.
Tufro-McReddie et al. (1992) studied this question.
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