Key result
Total vital capacity was significantly lower in persons who later had a first myocardial infarction compared to risk-factor-matched controls (3.17 vs. 3.29 liters; P<0.05).
Why the study?
Does diminished total vital capacity predict first myocardial infarction and sudden cardiac death?
Population
Persons who later had a first myocardial infarction or sudden cardiac death, and controls
Comparison
Diminished total vital capacity measured at… vs Normal or higher total vital capacity
Design
Case-control
Authors
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May support vital capacity as a risk marker for first MI; leaves open incremental value and needs prospective validation.
Case-Control
Does diminished total vital capacity predict first myocardial infarction and sudden cardiac death?
Absolute Event Rate: 3.17% vs 3.29%
p-value: p=<0.05
Diminished total vital capacity is an independent predictor of subsequent myocardial infarction and sudden cardiac death, even after adjusting for other risk factors.
Friedman et al. (1976) conducted a case-control in Myocardial infarction and sudden cardiac death. Total vital capacity vs. Controls was evaluated on Mean total vital capacity (p=<0.05). Total vital capacity was significantly lower in persons who later had a first myocardial infarction compared to risk-factor-matched controls (3.17 vs. 3.29 liters; P<0.05).
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