Key result
Echocardiographic evaluation in open chest dogs showed complete mitral valve opening occurred 0.044 sec before peak flow, while closing motion lagged behind mitral flow deceleration.
Population
17 open chest dogs
Design
Preclinical
Authors
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Canine mitral valve-flow timing should not guide clinical echo interpretation; leaves open human validation of these relationships.
This preclinical study details the physiological timing between echocardiographic mitral valve motion and actual transmitral flow, demonstrating that valve opening precedes peak flow while closing lags behind flow deceleration.
Laniado et al. (1975) studied this question. Echocardiographically recorded mitral valve motion vs. Phasic transmitral flow was evaluated on Timing of mitral valve opening and closing relative to phasic transmitral flow. Echocardiographic evaluation in open chest dogs showed complete mitral valve opening occurred 0.044 sec before peak flow, while closing motion lagged behind mitral flow deceleration.
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