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This study aims to compare the effects of metabolic syndrome and infectious burden on inflammation and coronary atherosclerosis severity.

The Effects of Metabolic Syndrome Versus Infectious Burden on Inflammation, Severity of Coronary Atherosclerosis, and Major Adverse Cardiovascular Events

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This study aims to compare the effects of metabolic syndrome and infectious burden on inflammation and coronary atherosclerosis severity.
Coronary angiography with Gensini score was used for 568 patients with coronary artery disease.
Metabolic syndrome score was defined using National Cholesterol Education Program criteria.
Infectious burden was measured by seropositivity to various agents.
Metabolic syndrome correlated significantly with plasma CRP and Gensini score (P < 0.001).
Metabolic syndrome increased risk of MACE with a hazard ratio of 1.51 (P < 0.001).
Plasma CRP concentration also increased MACE risk with a hazard ratio of 1.90 (P = 0.002).

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Randomized trial compares metabolic syndrome and infectious burden impact on inflammation and cardiovascular risk.

Dai et al. (2007) studied this question.

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