Key result
Permanent dual chamber pacing in hypertrophic cardiomyopathy decreased resting myocardial perfusion from 184 to 130 ml/min/100 g (P<0.05) and distributed perfusion reserve more homogeneously.
Why the study?
Does permanent dual chamber pacing improve myocardial perfusion in patients with symptomatic hypertrophic cardiomyopathy?
Population
n=6 patients with hypertrophic cardiomyopathy and severe symptoms of angina, and n=28 healthy volunteers.
Comparison
Permanent dual chamber pacemaker insertion. vs Baseline (sinus rhythm) and healthy volunteers.
Design
Cohort
Follow-up
3 months
Authors
Loading...
Associated with reduced resting perfusion in HCM; leaves open clinical benefit and requires prospective trials.
Does permanent dual chamber pacing improve myocardial perfusion in patients with symptomatic hypertrophic cardiomyopathy?
Absolute Event Rate: 130% vs 184%
p-value: p=<0.05
Permanent dual chamber pacing in symptomatic hypertrophic cardiomyopathy decreases resting myocardial blood flow and results in a more homogeneous distribution of myocardial perfusion reserve.
Posma et al. (1996) studied Hypertrophic cardiomyopathy (n=34). Permanent dual chamber pacing vs. Baseline (sinus rhythm) and healthy volunteers was evaluated on Absolute myocardial regional perfusion (ml/min/100 g) (p=<0.05). Permanent dual chamber pacing in hypertrophic cardiomyopathy decreased resting myocardial perfusion from 184 to 130 ml/min/100 g (P<0.05) and distributed perfusion reserve more homogeneously.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: