Key result
Men with NIDDM did not have increased intraperitoneal fat compared to controls (both averaged 11% of total body fat), but had higher truncal-to-peripheral fat ratios and greater insulin resistance.
Why the study?
Does regional adiposity, specifically intraperitoneal fat, differ between men with NIDDM and nondiabetic controls, and how does it relate to insulin sensitivity?
Case-Control (n=70)
Does regional adiposity, specifically intraperitoneal fat, differ between men with NIDDM and nondiabetic controls, and how does it relate to insulin sensitivity?
Absolute Event Rate: 11% vs 11%
Men with NIDDM do not have excess intraperitoneal fat compared to controls, but exhibit a fat distribution favoring truncal subcutaneous fat and a heightened state of insulin resistance at all adiposity levels.
No takes yet. Share an insight, caveat, or question.
Truncal fat distribution links to insulin resistance in NIDDM independent of intraperitoneal fat; leaves open causal mechanisms.
Abate et al. (1996) conducted a case-control in Non-Insulin-Dependent Diabetes Mellitus (NIDDM) (n=70). Mild NIDDM vs. Nondiabetic control subjects was evaluated on Intraperitoneal fat as a percentage of total body fat. Men with NIDDM did not have increased intraperitoneal fat compared to controls (both averaged 11% of total body fat), but had higher truncal-to-peripheral fat ratios and greater insulin resistance.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: